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Search Results for " α2a receptor "

17

Compounds

Cat No. Product Name Synonyms Targets
T2150 Guanfacine hydrochloride Tenex,Intuniv,Guanfacine Adrenergic Receptor
Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
T11894 Lusaperidone R107474 Adrenergic Receptor
Lusaperidone (R107474) is a potent α2-adrenergic receptor antagonist, a potential radioligand for the α (2)-adrenergic receptor, with inhibitory effects on α2A and α2C, with Ki values of 0.13 and 0.15 nM, respectively.
T6522 Guanabenz Acetate Wy8678 acetate,BR-750,Wytensin Adrenergic Receptor
Guanabenz Acetate (Wytensin) is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5, respectively.
T13804 OPC-28326 Adrenergic Receptor
OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively.
T3360 ZK 756326 ZK756326 2HCl CCR
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less ...
T12343 Benzquinamide BZQ,P2647,Benzoquinamide Adrenergic Receptor
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzqui...
T31602 Ecopipam Sch-39166,UNII-0X748O646K,Sch 39166 Dopamine Receptor
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and ...
T1735 Lurasidone hydrochloride Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 Dopamine Receptor , 5-HT Receptor , Norepinephrine
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag...
T26690 AVN-101 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
AVN-101 is a potent 5-HT7 receptor antagonist.
T22824 Guanfacine Others
Guanfacine is a selective agonist of the α2A receptor.
T60548 Guanoxabenz hydrochloride
Guanoxabenz (Hydroxyguanabenz) hydrochloride is an agonist of α2 adrenergic receptor. It has a Ki of 4000 nM and the fully activated form 40 nM for an α2A adrenoceptor[1][2][3].
T10264 AGN 192836 Others
AGN 192836 is a potent and selective α2 adrenergic agonist (EC50s: 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor).
T3278 Piribedil EU-4200,Trivastan,ET-495,Trivastal Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T35591 Guanfacine-13C,15N3 Guanfacine-13C,15N3
Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A...
T83956 CELT-133
CELT-133 is a selective fluorescent antagonist for the hα1A adrenergic receptor, demonstrating complete selectivity towards α1A over α2A receptors, with a Ki of 5 nM and 15% displacement at 1 μM in radioligand binding as...
T21446 Rotigotine Hydrochloride Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp...
T11286 Fiduxosin A 185980.1,ABT 980 Adrenergic Receptor
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin...
TargetMol